Interaction of schizophrenia and chronic cannabis use on reward anticipation sensitivity.

ABSTRACT: Chronic cannabis use and schizophrenia are both thought to affect reward processing. While behavioural and neural effects on reward processing have been investigated in both conditions, their interaction has not been studied, although chronic cannabis use is common among these patients. In the present study eighty-nine participants divided into four groups (control chronic cannabis users and non-users; schizophrenia patient cannabis users and non-users) performed a two-choice decision task, preceded by monetary cues (high/low reward/punishment or neutral), while being scanned using functional magnetic resonance imaging. Reward and punishment anticipation resulted in activation of regions of interest including the thalamus, striatum, amygdala and insula. Chronic cannabis use and schizophren

SUBMITTER: Fish S 

PROVIDER: S-EPMC8209034 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature