Association of Cannabis Use During Adolescence With Neurodevelopment.

ABSTRACT:

Importance

Animal studies have shown that the adolescent brain is sensitive to disruptions in endocannabinoid signaling, resulting in altered neurodevelopment and lasting behavioral effects. However, few studies have investigated ties between cannabis use and adolescent brain development in humans.

Objective

To examine the degree to which magnetic resonance (MR) imaging-assessed cerebral cortical thickness development is associated with cannabis use in a longitudinal sample of adolescents.

Design, setting, and participants

Data were obtained from the community-based IMAGEN cohort study, conducted across 8 European sites. Baseline data used in the present study were acquired from March 1, 2008, to December 31, 2011, and follow-up data were acquired from January 1, 2013

SUBMITTER: Albaugh MD 

PROVIDER: S-EPMC8209561 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature