Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance.
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ABSTRACT:
SUBMITTER: Stenhouse GE
PROVIDER: S-EPMC8209728 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
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Whole genome sequence analysis of <i>Shigella</i> from Malawi identifies fluoroquinolone resistance.
Stenhouse George E GE Jere Khuzwayo C KC Peno Chikondi C Bengtsson Rebecca J RJ Chinyama End E Mandolo Jonathan J Cain Amy A Iturriza-Gómara Miren M Bar-Zeev Naor N Cunliffe Nigel A NA Cornick Jennifer J Baker Kate S KS
Microbial genomics 20210501 5
Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant <i>Shigella</i> strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple <i>Shigella</i> isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant <i>qnrS1</i>. ...[more]
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