A Net Benefit Approach for the Optimal Allocation of a COVID-19 Vaccine.

ABSTRACT:

Objective

The objective of this study was to implement a model-based approach to identify the optimal allocation of a coronavirus disease 2019 (COVID-19) vaccine in the province of Alberta, Canada.

Methods

We developed an epidemiologic model to evaluate allocation strategies defined by age and risk target groups, coverage, effectiveness and cost of vaccine. The model simulated hypothetical immunisation scenarios within a dynamic context, capturing concurrent public health strategies and population behavioural changes.

Results

In a scenario with 80% vaccine effectiveness, 40% population coverage and prioritisation of those over the age of 60 years at high risk of poor outcomes, active cases are reduced by 17% and net monetary benefit increased by $263 million dollars,

SUBMITTER: Kirwin E 

PROVIDER: S-EPMC8209775 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature