Clinical characteristics and treatment outcomes of patients with MDR tuberculosis in Dar Es Salaam region, Tanzania.

ABSTRACT:

Background

In Tanzania more than 28% of all multi-drug resistant tuberculosis (MDR-TB) cases occur in Dar es Salaam. However, information about management and clinical outcomes of patients with MDR-TB in the region is scarce, and hence the need for this study.

Methods

A 5-year retrospective cohort study was conducted in six centres in Dar es Salaam. Descriptive statistics were used to summarize social demographics and clinical characteristics. Associations between occurrence of adverse events, regimen change and cure were determined using the Chi-square test whereas factors associated with mortality were determined using the Log-ranking test and Cox regression model.

Results

Three-hundred patient files were found and reviewed. The majority were male 199 (66.3%), aged

SUBMITTER: Myemba DT 

PROVIDER: S-EPMC8210025 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature