Phenotypic and genotypic antimicrobial resistance in clinical anaerobic isolates from India.

ABSTRACT:

Background

Antimicrobial resistance (AMR) in anaerobes remains a neglected field. The laborious procedures, non-compliance with the standard methodology and differences in interpretive breakpoints add variation in resistance data.

Objectives

To assess the phenotypic and genotypic resistance among clinically important anaerobes to six antibiotics frequently used as empirical therapy for anaerobic infections.

Methods

A total of 150 anaerobic isolates were recovered from clinical specimens. The antimicrobial susceptibility was determined by the breakpoint agar dilution method as per CLSI guidelines. The presence of genes encoding resistance to metronidazole (nim gene), imipenem (cfiA gene) and mobilizable insertion sequence (IS) elements was detected to com

SUBMITTER: Sood A 

PROVIDER: S-EPMC8210138 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature