New Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Zn(II), Cd(II), and Hg(II) Gibberellate Complexes: Synthesis, Structure, and Inhibitory Activity Against COVID-19 Protease.

ABSTRACT: Transition metals such as Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Zn(II), Cd(II), and Hg(II) have been reacted with gibberellic acid (HGA) to give novel complexes, and those have been characterized by physical, spectral and analytical methods. The plant hormone gibberellate acts as a deprotonated bidentate ligand in the complexation reaction with central metal ions in the ratio 1 : 2 (M ⁿ⁺ : GA). The complexes [M(GA)₂(H₂O)₂], where [M = Mn(II), Co(II), and Ni(II)] form octahedral structures, while [M(GA)₂] complexes [M = Zn(II), Cd(II), and Hg(II)] display four-coordination geometry. The octahedral structures of Cr(III) and Fe(III) complexes are characterized by the general formula [M(GA)₂(H₂O)(Cl)]. Comp

SUBMITTER: Refat MS 

PROVIDER: S-EPMC8210501 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature