Mechanical power normalized to lung-thorax compliance predicts prolonged ventilation weaning failure: a prospective study.

ABSTRACT:

Background

Mechanical power (MP) of artificial ventilation, the energy transferred to the respiratory system, is a chief determinant of adequate oxygenation and decarboxylation. Calculated MP, the product of applied airway pressure and minute ventilation, may serve as an estimate of respiratory muscle workload when switching to spontaneous breathing. The aim of the study was to assess MP's discriminatory performance in predicting successful weaning from prolonged tracheostomy ventilation.

Methods

Prospective, observational study in 130 prolonged mechanically ventilated, tracheotomized patients in a specialized weaning center. Predictive weaning outcome ability of arterial blood gas analyses and indices derived from calculated MP at beginning and end of weaning was determined

SUBMITTER: Ghiani A 

PROVIDER: S-EPMC8210735 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature