Building a stem cell-based primate uterus.
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ABSTRACT:
SUBMITTER: Bergmann S
PROVIDER: S-EPMC8211708 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Publications
Building a stem cell-based primate uterus.
Bergmann Sophie S Schindler Magdalena M Munger Clara C Penfold Christopher A CA Boroviak Thorsten E TE
Communications biology 20210617 1
The uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births. However, in vitro models focusing on the uterine tissue itself would allow modelling of pathologies including endometriosis and uterine cancers, and open new avenues to investigate embryo implantation and human development. Motivated by these key questions, we discuss how st ...[more]
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