Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial.

ABSTRACT: Breast cancer risk reduction has been validated by large-scale clinical trials, but uptake remains low. A risk communication tool could provide personalized risk-reduction information for high-risk women. A low-literacy-friendly, visual, and personalized tool was designed as part of the Women Informed to Screen Depending On Measures of risk (WISDOM) study. The tool integrates genetic, polygenic, and lifestyle factors, and quantifies the risk-reduction from undertaking medication and lifestyle interventions. The development and design process utilized feedback from clinicians, decision-making scientists, software engineers, and patient advocates. We piloted the tool with 17 study participants, collecting quantitative and qualitative feedback. Overall, participants felt they better understoo

SUBMITTER: Keane H 

PROVIDER: S-EPMC8211836 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature