Association of IL-16 rs11556218 T/G polymorphism with the risk of developing type 2 diabetes mellitus.

ABSTRACT:

Introduction

Diabetes mellitus is a chronic disorder that has serious complications. Type 2 diabetes mellitus is more widespread worldwide and in Egypt. Interleukin-16 is a pro-inflammatory factor that can lead to many inflammatory diseases by stimulating the secretions of cytokines. Inflammation and obesity are concomitant factors that may lead to insulin resistance and type 2 diabetes mellitus. In this study, we tried to focus on the relation between Interleukin-16 rs11556218 polymorphism and the risk of development of type 2 diabetes mellitus.

Patients and methods

128 type 2 diabetic patients and 128 healthy individuals as control were included in this case-control study. Interleukin-16 gene polymorphism (SNP rs11556218 T/G) was genotyped using a real-time polymerase chai

SUBMITTER: Mohammad DG 

PROVIDER: S-EPMC8212215 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature