Copper and zinc concentrations in the breast milk of mothers undergoing treatment for Wilson's disease: a prospective study.

ABSTRACT:

Objective

To evaluate the concentrations of copper and zinc in the breast milk of mothers undergoing treatment for Wilson's disease (WD) and clarify whether they can safely breast feed their infants.

Design

This was an observational and prospective study in an individual-based case series.

Setting

Breast milk samples were collected from participants across Japan from 2007 to 2018 at the Department of Pediatrics, Teikyo University in Tokyo. This was a primary-care level study. Clinical data were collected from the participants' physicians.

Patients

Eighteen Japanese mothers with WD who were treated with trientine, penicillamine or zinc, and 25 healthy mothers as controls, were enrolled.

Main outcome measures

Whey exacted from the milk was used to evaluate

SUBMITTER: Kodama H 

PROVIDER: S-EPMC8212407 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature