Hospital-based prospective study of pertussis in infants and close contacts in Tehran, Iran.

ABSTRACT:

Background

Pertussis remain a global health concern, especially in infants too young to initiate their vaccination. Effective vaccination and high coverage limit the circulation of the pathogen, yet duration of protection is limited and boosters are recommended during a lifetime. In Iran, boosters are given at 18 months and 6 years old using whole pertussis vaccines for which efficacy is not known, and pertussis surveillance is scant with only sporadic biological diagnosis. Burden of pertussis is not well understood and local data are needed.

Methods

Hospital-based prospective study implementing molecular laboratory testing in infants aged ≤6 months and presenting ≥5 days of cough associated to one pertussis-like symptom in Tehran. Household and non-household contact cases o

SUBMITTER: Noel G 

PROVIDER: S-EPMC8212501 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature