Radiomics Analysis of Contrast-Enhanced CT for Hepatocellular Carcinoma Grading.

ABSTRACT:

Objectives

To investigate the value of contrast-enhanced computer tomography (CT)-based on radiomics in discriminating high-grade and low-grade hepatocellular carcinoma (HCC) before surgery.

Methods

The retrospective study including 161 consecutive subjects with HCC which was approved by the institutional review board, and the patients were divided into a training group (n = 112) and test group (n = 49) from January 2013 to January 2018. The least absolute shrinkage and selection operator (LASSO) was used to select the most valuable features to build a support vector machine (SVM) model. The performance of the predictive model was evaluated using the area under the curve (AUC), accuracy, sensitivity, and specificity.

Results

The SVM model showed an acceptable ability

SUBMITTER: Chen W 

PROVIDER: S-EPMC8212783 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature