The effects of caffeine in adults with neurogenic orthostatic hypotension: a systematic review.

ABSTRACT:

Purpose

To systematically review the evidence base for the effectiveness and safety of caffeine for the treatment of neurogenic orthostatic hypotension in adults.

Methods

Eight electronic databases were searched in January 2021. Original research studies or case reports involving adults with neurogenic orthostatic hypotension were included if caffeine was an intervention and outcomes included symptoms, blood pressure or adverse effects. Relevant studies were screened and underwent qualitative analysis. Insufficient reporting precluded meta-analysis.

Results

Five studies were identified: four crossover studies and one case report summation. Study size ranged from 5 to 16 participants. Participants had neurogenic orthostatic hypotension, with a mean standing systolic bl

SUBMITTER: Gibbon JR 

PROVIDER: S-EPMC8212790 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature