Serum Anti-Mullerian Hormone Levels Were Negatively Associated With Body Fat Percentage in PCOS Patients.

ABSTRACT:

Background

Obesity is a state of excess body fat accumulation, and appears to be closely associated with polycystic ovary syndrome (PCOS). Notably, plausible biological pathways through which obesity can regulate anti-Müllerian hormone (AMH) production have been proposed, and women with PCOS characteristically have an increased AMH level. Body fat accumulation can be described by body fat percentage (BFP). However, the relationship between BFP and AMH still remains unclear.

Materials and methods

A total of 87 controls and 156 PCOS patients were divided into lean and overweight/obese groups, and the PCOS patients were further divided into hyper-AMH and normal-AMH subgroups. Univariate regression was used to assess the unadjusted relationship between AMH and outcome variables,

SUBMITTER: Luo E 

PROVIDER: S-EPMC8213015 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature