Quantifying frequency content in cross-sectional retinal scans of diabetics vs. controls.

ABSTRACT:

Purpose

To examine subtle differences in the structure of diabetic vs. control retinas.

Methods

Spectral-domain optical coherence tomography (SD-OCT) images were compared for the retinas of 33 diabetic subjects who did not have clinical evidence of diabetic macular edema and age-matched controls, with central macular thicknesses of 275 and 276 microns, respectively. Cross-sectional retinal images through the fovea, called B-scans, were analyzed for spatial frequency content. The B-scans were processed to remove and smooth the portions of the retinal image not within regions of interest in the retina. The remaining retinal images were then quantified using a Fast Fourier Transform (FFT) approach that provided amplitude as a function of spatial frequency.

Results

The FF

SUBMITTER: Papay JA 

PROVIDER: S-EPMC8213050 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature