Regional sequencing collaboration reveals persistence of the T12 <i>Vibrio cholerae</i> O1 lineage in West Africa.

ABSTRACT:

Background

Despite recent insights into cholera transmission patterns in Africa, regional and local dynamics in West Africa-where cholera outbreaks occur every few years-are still poorly understood. Coordinated genomic surveillance of Vibrio cholerae in the areas most affected may reveal transmission patterns important for cholera control.

Methods

During a regional sequencing workshop in Nigeria, we sequenced 46 recent V. cholerae isolates from Cameroon, Niger, and Nigeria (37 from 2018 to 2019) to better understand the relationship between the V. cholerae bacterium circulating in these three countries.

Results

From these isolates, we generated 44 whole Vibrio cholerae O1 sequences and analyzed them in the context of 1280 published V. ch

SUBMITTER: Ekeng E 

PROVIDER: S-EPMC8213408 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature