Clinical and Kinematic Features of Valproate-Induced Tremor and Differences with Essential Tremor.

ABSTRACT: Tremor is a common movement disorder that can be induced by medications, including valproate, which is used for the treatment of epilepsy. However, the clinical and neurophysiological features of valproate-induced tremor are still under-investigated. We performed a clinical and kinematic assessment of valproate-induced tremor by considering tremor body distribution and activation conditions. We investigated possible correlations between demographic and clinical data and kinematic features. Valproate-induced tremor results were also compared with those collected in a large sample of patients with essential tremor. Sixteen valproate-induced tremor patients and 93 essential tremor patients were enrolled. All participants underwent a standardised neurological examination and video recording. P

SUBMITTER: Paparella G 

PROVIDER: S-EPMC8213593 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature