Localized surface plasmon resonance inflection points for improved detection of chemisorption of 1-alkanethiols under total internal reflection scattering microscopy.

ABSTRACT: Plasmonic gold nanoparticles are widely used in localized surface plasmon resonance (LSPR) sensing. When target molecules adsorb to the nanoparticles, they induce a shift in the LSPR scattering spectrum. In conventional LSPR sensing, this shift is monitored at the maximum of the LSPR scattering peak. Herein, we describe the sensitivity of detecting chemisorption of 1-alkanethiols with different chain lengths (1-butanethiol and 1-haxanethiol) on single gold nanorods (AuNRs) of fixed diameter (25 nm) and three different aspect ratios under a total internal reflection scattering microscope. For single AuNRs of all sizes, the inflection point (IF) at the long-wavelength side (or low-energy side) of the LSPR scattering peak showed higher detection sensitivity than the traditionally used peak ma

SUBMITTER: Ryu KR 

PROVIDER: S-EPMC8213723 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature