Increased risk of stroke among patients with inflammatory bowel disease: A PRISMA-compliant meta-analysis.

ABSTRACT:

Background

Previous studies on the association between inflammatory bowel disease (IBD) and stroke showed conflicting results.

Methods

Articles published before July 2020 were searched in databases (PubMed, Web of Science, Medline, EMBASE, and Google Scholar). We computed all multivariate odds ratios (ORs) or relative risks (RRs) and 95% confidence intervals (CI) by using STATA 12.0 software.

Results

The meta-analysis indicated that IBD was associated with an elevated risk of stroke (OR/RR = 1.21, 95% CI 1.08 to 1.34, I²  = 83.6%, p < .001). In addition, both Crohn's disease (CD) and ulcerative colitis (UC) were associated with a higher risk of stroke (CD: OR/RR = 1.25, 95% CI 1.03 to 1.52, I²  = 86.1%, p < .001; UC: OR/RR = 1.09, 95% CI 1.04 to

SUBMITTER: Chen Y 

PROVIDER: S-EPMC8213927 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature