Online database for brain cancer-implicated genes: exploring the subtype-specific mechanisms of brain cancer.

ABSTRACT:

Background

Brain cancer is one of the eight most common cancers occurring in people aged 40+ and is the fifth-leading cause of cancer-related deaths for males aged 40-59. Accurate subtype identification is crucial for precise therapeutic treatment, which largely depends on understanding the biological pathways and regulatory mechanisms associated with different brain cancer subtypes. Unfortunately, the subtype-implicated genes that have been identified are scattered in thousands of published studies. So, systematic literature curation and cross-validation could provide a solid base for comparative genetic studies about major subtypes.

Results

Here, we constructed a literature-based brain cancer gene database (BCGene). In the current release, we have a collection of 1421 uniq

SUBMITTER: Zhao M 

PROVIDER: S-EPMC8214279 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature