HPV molecular detection from urine versus cervical samples: an alternative for HPV screening in indigenous populations.

ABSTRACT:

Background

Cervical cancer (CC) is the fourth leading cause of death from neoplasms in women and is caused by the human papilloma virus (HPV). Several methods have been developed for the screening of cervical lesions and HPV; however, some socio-cultural factors prevent women from undergoing gynecological inspection, which results in a higher risk of mortality from cervical cancer in certain population groups as indigenous communities. This study aimed to compare the concordance in HPV detection from urine and cervical samples, to propose an alternative to cervical scraping, which is commonly used in the cervical cancer screening.

Methodology

The DNA from cervical scrapings and urine samples was extracted using the proteinase K method followed by precipitation with alcohol,

SUBMITTER: Torres-Rojas FI 

PROVIDER: S-EPMC8214846 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature