Distribution and overlap of entorhinal, premotor, and amygdalar connections in the monkey anterior cingulate cortex.

ABSTRACT: The anterior cingulate cortex (ACC) is important for decision-making as it integrates motor plans with affective and contextual limbic information. Disruptions in these networks have been observed in depression, bipolar disorder, and post-traumatic stress disorder. Yet, overlap of limbic and motor connections within subdivisions of the ACC is not well understood. Hence, we administered a combination of retrograde and anterograde tracers into structures important for contextual memories (entorhinal cortex), affective processing (amygdala), and motor planning (dorsal premotor cortex) to assess overlap of labeled projection neurons from (outputs) and axon terminals to (inputs) the ACC of adult rhesus monkeys (Macaca mulatta). Our data show that entorhinal and dorsal premotor cortical (dPMC) c

SUBMITTER: Calderazzo SM 

PROVIDER: S-EPMC8214921 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature