Association of TCF7L2 rs7903146 Polymorphism with the Risk of Type 2 Diabetes Mellitus (T2DM) Among Kurdish Population in Erbil Province, Iraq.

ABSTRACT: The genetic predispositions responsible for developing type 2 diabetes mellitus (T₂DM) in the Middle East are poorly understood. The rs7903146 single nucleotide polymorphism (SNP) located in transcription factor 7-like-2 (TCF7L2) gene has been recognized to have a vital role in the development of T₂DM disorder. The current study is the first to have researched the possible association between TCF7L2 rs7903146 SNP and T₂DM among Kurdish population in Kurdistan region of Iraq. The study included 212 participants, half of them were T₂DM patients, and the other half were disease-free and normoglycemic controls. Genotyping was performed by using a high throughput cost and time effective tetra-primer amplification refractory mutation syst

SUBMITTER: Mustafa S 

PROVIDER: S-EPMC8215002 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature