Cost-effectiveness of five versus ten years of alendronate treatment prior to drug holiday for women with osteoporosis.

ABSTRACT: We performed a cost-effectiveness analysis comparing 5 versus 10 years of alendronate treatment prior to 5-year drug holiday for US postmenopausal women with hip BMD T-scores between - 2.5 and - 3.5. We found that for most postmenopausal women 5 years of treatment prior to drug holiday is the more effective and cost-effective option.

Introduction

We performed a cost-effectiveness analysis to compare 5 versus 10 years of alendronate treatment prior to 5-year drug holiday for postmenopausal osteoporotic women.

Methods

We created an individual-level state-transition microsimulation model to compare 3 treatment strategies for US postmenopausal women with osteoporosis and femoral neck BMD T-scores between - 2.5 and - 3.5 at baseline: recurrent periods of 5 years of alendronate fol

SUBMITTER: Nayak S 

PROVIDER: S-EPMC8215100 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature