Effects of Vitamin D₂ and 25-Hydroxyvitamin D₂ Supplementation on Plasma Vitamin D Epimeric Metabolites in Adult Cats.

ABSTRACT: Feline vitamin D status is based on dietary consumption but metabolism of this essential nutrient and the efficacy of supplementation forms are poorly described in cats. The aim of this study was to further elucidate the metabolites of vitamin D₂ in cats and to compare the effectiveness of vitamin D₂ and 25(OH)D₂ for increasing feline vitamin D status. Eight adult male castrated domestic shorthair cats received vitamin D₂ or 25(OH)D₂ in a single crossover design. Vitamin D₂ was dosed daily in a molar equivalent dosage to vitamin D₃ ingested in the diet while 25(OH)D₂ was provided at a daily dose of 20% molar equivalent intake of dietary vitamin D₃ based on its expected higher potency. Plasma

SUBMITTER: Ruggiero CE 

PROVIDER: S-EPMC8215352 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature