Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO₂): A Pilot Study.

ABSTRACT: Astronauts on board the International Space Station (ISS) must adapt to several environmental challenges including microgravity, elevated carbon dioxide (CO₂), and isolation while performing highly controlled movements with complex equipment. Head down tilt bed rest (HDBR) is an analog used to study spaceflight factors including body unloading and headward fluid shifts. We recently reported how HDBR with elevated CO₂ (HDBR+CO₂) affects visuomotor adaptation. Here we expand upon this work and examine the effects of HDBR+CO₂ on brain activity during visuomotor adaptation. Eleven participants (34 ± 8 years) completed six functional MRI (fMRI) sessions pre-, during, and post-HDBR+CO₂. During fMRI, participants completed a visuomotor adapta

SUBMITTER: Salazar AP 

PROVIDER: S-EPMC8215599 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature