TSH Mediated the Effect of Iodized Salt on Child Cognition in a Randomized Clinical Trial.

ABSTRACT:

Objectives

This study examines the hormonal mediators of the effect of iodized salt in pregnancy on child cognition.

Methods

Sixty districts across 6 zones in the Amhara region of Ethiopia were randomly allocated to a control or intervention arm of early market access to iodized salt. Twenty-two villages per arm were randomly selected for this sub-study. A total of 1220 pregnant women who conceived after the intervention began were enrolled and assessed for their iodine and iron status. Data were collected once on the household socio-demographic status and iodized salt use, and maternal urinary iodine during pregnancy. Then, infants' diet, urinary iodine level, cognitive development (Bayley III), serum hormonal levels, iron status, and inflammation markers were measured betw

SUBMITTER: Mohammed H 

PROVIDER: S-EPMC8216409 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature