Staphylococcus saprophyticus From Clinical and Environmental Origins Have Distinct Biofilm Composition.

ABSTRACT: Biofilm formation has been shown to be critical to the success of uropathogens. Although Staphylococcus saprophyticus is a common cause of urinary tract infections, its biofilm production capacity, composition, genetic basis, and origin are poorly understood. We investigated biofilm formation in a large and diverse collection of S. saprophyticus (n = 422). Biofilm matrix composition was assessed in representative strains (n = 63) belonging to two main S. saprophyticus lineages (G and S) recovered from human infection, colonization, and food-related environment using biofilm detachment approach. To identify factors that could be associated with biofilm formation and structure variation, we used a pangenome-wide association study approach. Almost all the is

SUBMITTER: Lawal OU 

PROVIDER: S-EPMC8216562 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature