Comparative Risks of Nonsteroidal Anti-Inflammatory Drugs on CKD.

ABSTRACT:

Background and objectives

There have been doubts about the association between nonsteroidal anti-inflammatory drug use and worsening kidney function, and whether there is a difference between risks of individual nonsteroidal anti-inflammatory drugs is presently unclear. Therefore, this study aimed to evaluate the association between nonsteroidal anti-inflammatory drug exposure and the risk of incident eGFR <60 ml/min per 1.73 m² and compare the risks between nonsteroidal anti-inflammatory drug subtypes in the Chinese population.

Design, setting, participants, & measurements

From 2008 to 2017, a total of 1,982,488 subjects aged 18 years or older with baseline eGFR ≥60 ml/min per 1.73 m² were enrolled in this retrospective cohort study. Multivariable Cox

SUBMITTER: Wan EYF 

PROVIDER: S-EPMC8216605 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature