Association of Depressive Symptoms with Rapid Kidney Function Decline in Adults with Normal Kidney Function.

ABSTRACT:

Background and objectives

The relationship of depressive symptoms with kidney function remains poorly investigated. We aimed to evaluate the prospective association between depressive symptoms and rapid decline in kidney function in Chinese adults with normal kidney function.

Design, setting, participants, & measurements

A total of 4763 participants with eGFR≥60 ml/min per 1.73 m² at baseline were enrolled from the China Health and Retirement Longitudinal Study. Baseline depressive symptoms were determined using a ten-item Center for Epidemiologic Studies Depression scale with a cutoff score of greater than or equal to ten to define high depressive symptoms. The GFR was estimated by a combination of serum creatinine and cystatin C. The primary outcome was rapid de

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC8216614 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature