Associations Between Serum Free Fatty Acid Levels and Incident Diabetes in a 3-Year Cohort Study.

ABSTRACT:

Purpose

High circulating free fatty acid (FFA) is associated with the development of diabetes. This study was designed to evaluate longitudinal associations between FFA levels, changes in FFA levels, and mean FFA levels and incident diabetes.

Participants and methods

This 3-year cohort study was conducted in Ningyang between 2011 and 2014. Serum FFA, fasting blood glucose (FPG), 2-hour postprandial blood glucose (2hPG), and glycosylated hemoglobin (HbA1c) levels were measured at baseline and at the end of follow-up. A multivariate stepwise logistic regression model was used to evaluate associations between serum FFA levels in various groups and the risk of incident diabetes.

Results

Of the 2905 individuals without baseline diabetes, 290 developed diabetes by the 3-yea

SUBMITTER: Li Q 

PROVIDER: S-EPMC8216696 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature