Reticular Pseudodrusen in Late-Onset Retinal Degeneration.

ABSTRACT:

Purpose

To characterize the association of reticular pseudodrusen (RPD) with late-onset retinal degeneration (L-ORD) using multimodal imaging.

Design

Prospective, 2-center, longitudinal case series.

Participants

Twenty-nine patients with L-ORD.

Methods

All patients were evaluated within a 3-year interval with near-infrared reflectance, fundus autofluorescence, and spectral-domain OCT. In addition, a subset of patients also underwent indocyanine green angiography, fundus fluorescein angiography, mesopic microperimetry, and multifocal electroretinography.

Main outcome measures

Prevalence, topographic distribution, and temporal phenotypic changes of RPD in L-ORD.

Results

A total of 29 patients with molecularly confirmed L-ORD were included in this pr

SUBMITTER: Borooah S 

PROVIDER: S-EPMC8217414 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature