External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients.

ABSTRACT:

Importance

The Epic Sepsis Model (ESM), a proprietary sepsis prediction model, is implemented at hundreds of US hospitals. The ESM's ability to identify patients with sepsis has not been adequately evaluated despite widespread use.

Objective

To externally validate the ESM in the prediction of sepsis and evaluate its potential clinical value compared with usual care.

Design, setting, and participants

This retrospective cohort study was conducted among 27 697 patients aged 18 years or older admitted to Michigan Medicine, the academic health system of the University of Michigan, Ann Arbor, with 38 455 hospitalizations between December 6, 2018, and October 20, 2019.

Exposure

The ESM score, calculated every 15 minutes.

Main outcomes and measures

Sepsis, as de

SUBMITTER: Wong A 

PROVIDER: S-EPMC8218233 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature