Free-breathing abdominal T₁ mapping using an optimized MR fingerprinting sequence.

ABSTRACT: In this work, we propose a free-breathing magnetic resonance fingerprinting (MRF) method that can be used to obtain B₁ ⁺ -robust quantitative T₁ maps of the abdomen in a clinically acceptable time. A three-dimensional MRF sequence with a radial stack-of-stars trajectory was implemented, and its k-space acquisition ordering was adjusted to improve motion-robustness in the context of MRF. The flip angle pattern was optimized using the Cramér-Rao Lower Bound, and the encoding efficiency of sequences with 300, 600, 900 and 1800 flip angles was evaluated. To validate the sequence, a movable multicompartment phantom was developed. Reference multiparametric maps were acquired under stationary conditions using a previously validated MRF method. Periodic motion of t

SUBMITTER: van Riel MHC 

PROVIDER: S-EPMC8218311 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature