Limited recurrence distance of glioblastoma under modern radiotherapy era.

ABSTRACT:

Background

The optimal treatment volume for Glioblastoma multiforme (GBM) is still a subject of debate worldwide. The current study was aimed to determine the distances between recurring tumors and the edge of primary lesions, and thereby provide evidence for accurate target area delineation.

Methods

Between October 2007 and March 2019, 68 recurrent patients with GBM were included in our study. We measured the distance from the initial tumor to the recurrent lesion of GBM patients by expanding the initial gross tumor volume (GTV) to overlap the center of recurrent lesion, with the help of the Pinnacle Treatment Planning System.

Results

Recurrences were local in 47(69.1%) patients, distant in 12(17.7%) patients, and both in 9(13.2%) patients. Factors significantly infl

SUBMITTER: Tu Z 

PROVIDER: S-EPMC8218451 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature