Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma.

ABSTRACT:

Objective

Evaluate the oncologic outcomes and cost analysis of transitioning to a specimen oriented intraoperative margin assessment protocol from a tumour bed sampling protocol in oral cavity (OCSCC) and oropharyngeal squamous cell carcinoma (OPSCC).

Study design

Retrospective case series and subsequent prospective cohort study SETTING: Tertiary care academic teaching hospital SUBJECTS AND METHODS: Retrospective case series of all institutional T1-T2 OCSCC or OPSCC treated with primary surgery between January 1st 2009 - December 31st 2014. Kaplan-Meier survival estimates with log rank tests were used to compare patients based on final margin status. Cost analysis was performed for escalation of therapy due to positive final margins. Following introduction of a specimen deri

SUBMITTER: Horwich P 

PROVIDER: S-EPMC8218466 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature