Occupational exposure to polycyclic aromatic hydrocarbons and risk of prostate cancer.

ABSTRACT:

Background

Several industries entailing exposure to polycyclic aromatic hydrocarbons (PAHs) are known or suspected carcinogens. A handful of studies have assessed the role of PAHs exposure in prostate cancer risk, but none has examined tumor aggressiveness or the influence of screening practices and detection issues. We aimed to examine the association between lifetime occupational exposure to PAHs and prostate cancer risk.

Methods

Detailed work histories were collected from 1,929 prostate cancer cases (436 aggressive) and 1,994 controls from Montreal, Canada (2005-2012). Industrial hygienists applied the hybrid expert approach to assign intensity, frequency and certainty of exposure to benzo[a]pyrene, PAHs from wood, coal, petroleum, other sources, and any source, in each j

SUBMITTER: Barul C 

PROVIDER: S-EPMC8218525 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature