Ontology highlight
ABSTRACT:
SUBMITTER: Wang Q
PROVIDER: S-EPMC8218640 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Wang Qian Q Peng Kai K Liu Yuan Y Xiao Xia X Wang Zhiqiang Z Li Ruichao R
Antimicrobial agents and chemotherapy 20210617 7
The emergence and transmission of novel antimicrobial resistance genes pose a great threat to public health globally. Recently, the plasmid-encoding RND efflux pump TMexCD1-TOprJ1 in Klebsiella pneumoniae was reported to reduce the sensitivity of multiple antimicrobials. Here, we identified a pandrug-resistant Proteus mirabilis isolate that harbored the novel <i>tmexCD3-toprJ3</i> gene cluster located on SXT/R391 ICE. This study expands current knowledge of the transfer mechanisms of <i>tmexCD1- ...[more]