MetamORF: a repository of unique short open reading frames identified by both experimental and computational approaches for gene and metagene analyses.

ABSTRACT: The development of high-throughput technologies revealed the existence of non-canonical short open reading frames (sORFs) on most eukaryotic ribonucleic acids. They are ubiquitous genetic elements conserved across species and suspected to be involved in numerous cellular processes. MetamORF (https://metamorf.hb.univ-amu.fr/) aims to provide a repository of unique sORFs identified in the human and mouse genomes with both experimental and computational approaches. By gathering publicly available sORF data, normalizing them and summarizing redundant information, we were able to identify a total of 1 162 675 unique sORFs. Despite the usual characterization of ORFs as short, upstream or downstream, there is currently no clear consensus regarding the definition of these categories. Thus, the dat

SUBMITTER: Choteau SA 

PROVIDER: S-EPMC8218702 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature