Hepatitis C in Uganda: Identification of infected blood donors for micro-elimination.

ABSTRACT:

Background

The drive to eliminate viral hepatitis by 2030 is underway. However, locally generated data on active infection is required to focus such efforts. We performed a regionally-inclusive survey to determine prevalence of active HCV, genotypes and related factors among Ugandan blood donors.

Methods

Participants from regional blood banks and blood collection centers were surveyed for information on demographic, clinical and lifestyle factors. Blood was assayed for HCV infection, HCV genotypes and subtypes. Logistic regression was performed to determine factors associated with active HCV infection.

Results

Of 1243 participants, 1041 (83.7%) were male, average age (SD), 27.7 (9.8). Prevalence of active HCV infection was 7.8% and we identified 3 genotypes. Median ag

SUBMITTER: Nankya-Mutyoba J 

PROVIDER: S-EPMC8219885 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature