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Bioinspired Nucleophilic Attack on a Tungsten-Bound Acetylene: Formation of Cationic Carbyne and Alkenyl Complexes.

ABSTRACT: Inspired by the proposed inner-sphere mechanism of the tungstoenzyme acetylene hydratase, we have designed tungsten acetylene complexes and investigated their reactivity. Here, we report the first intermolecular nucleophilic attack on a tungsten-bound acetylene (C₂H₂) in bioinspired complexes employing 6-methylpyridine-2-thiolate ligands. By using PMe₃ as a nucleophile, we isolated cationic carbyne and alkenyl complexes.

SUBMITTER: Ehweiner MA

PROVIDER: S-EPMC8220502 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Bioinspired Nucleophilic Attack on a Tungsten-Bound Acetylene: Formation of Cationic Carbyne and Alkenyl Complexes.

Ehweiner Madeleine A MA Peschel Lydia M LM Stix Niklas N Ćorović Miljan Z MZ Belaj Ferdinand F Mösch-Zanetti Nadia C NC

Inorganic chemistry 20210414 12

Inspired by the proposed inner-sphere mechanism of the tungstoenzyme acetylene hydratase, we have designed tungsten acetylene complexes and investigated their reactivity. Here, we report the first intermolecular nucleophilic attack on a tungsten-bound acetylene (C2H2) in bioinspired complexes employing 6-methylpyridine-2-thiolate ligands. By using PMe3 as a nucleophile, we isolated cationic carbyne and alkenyl complexes. ...[more]

PMID: 33852290

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