Drug repurposing for COVID-19: Approaches, challenges and promising candidates.

ABSTRACT: Traditional drug development and discovery has not kept pace with threats from emerging and re-emerging diseases such as Ebola virus, MERS-CoV and more recently, SARS-CoV-2. Among other reasons, the exorbitant costs, high attrition rate and extensive periods of time from research to market approval are the primary contributing factors to the lag in recent traditional drug developmental activities. Due to these reasons, drug developers are starting to consider drug repurposing (or repositioning) as a viable alternative to the more traditional drug development process. Drug repurposing aims to find alternative uses of an approved or investigational drug outside of its original indication. The key advantages of this approach are that there is less developmental risk, and it is less time-consu

SUBMITTER: Ng YL 

PROVIDER: S-EPMC8220862 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature