Sensitization against Fungi in Patients with Airway Allergies over 20 Years in Germany.

ABSTRACT:

Background

Fungal spores are ubiquitous allergens. Severe forms of asthma are particularly highly associated with fungal sensitization. National and international asthma guidelines recommend the implementation of allergen immunotherapy if indicated. Thus, detection and treatment of relevant allergies are key components of primary care of these patients.

Objectives

The aims of the study were (i) to investigate trends in the prevalence of sensitization to twelve fungi in central Germany over the last 20 years and (ii) to dissect specific sensitization patterns among the 3 most important fungi: Aspergillus, Alternaria, and Cladosporium.

Methods

This single-center study evaluated skin prick test (SPT) results of 3,358 patients with suspected airway allergies over a period

SUBMITTER: Forkel S 

PROVIDER: S-EPMC8220924 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature