Identifying Responders and Exploring Mechanisms of Action of the Endobronchial Coil Treatment for Emphysema.

ABSTRACT:

Background

So far, 3 randomized controlled trials have shown that the endobronchial treatment using coils is safe and effective. However, the more exact underlying mechanism of the treatment and best predictors of response are unknown.

Objectives

The aim of the study was to gain more knowledge about the underlying physiological mechanism of the lung volume reduction coil treatment and to identify potential predictors of response to this treatment.

Methods

This was a prospective nonrandomized single-center study which included patients who were bilaterally treated with coils. Patients underwent an extensive number of physical tests at baseline and 3 months after treatment.

Results

Twenty-four patients (29% male, mean age 62 years, forced expiratory volume in 1 s

SUBMITTER: Hartman JE 

PROVIDER: S-EPMC8220926 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature