Sedentary work and breast cancer risk: A systematic review and meta-analysis.

ABSTRACT:

Objectives

This systematic review and meta-analysis aimed to assess sedentary work's contribution to breast cancer risk quantitatively using thorough research articles.

Methods

We performed a meta-analysis using a registered protocol in PROSPERO (registration number: CRD42020204629). Literature from PubMed, Embase, and Cochrane involving sedentary work and breast cancer risk was reviewed. We calculated the overall pooled risk ratios (RRs) and 95% CI with a random-effect model from the included studies. Furthermore, we performed stratified analyses by characteristics of studies.

Results

Thirty-one studies (13 cohort studies and 18 case-control studies) were included in the analysis. The overall effect of the pooled analysis was an RR of 1.16 (95% CI 1.08-1.23). The res

SUBMITTER: Lee J 

PROVIDER: S-EPMC8221371 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature