Ozone exposure during early pregnancy and preterm birth: A systematic review and meta-analysis.

ABSTRACT: Exposure to ozone has been linked to reproductive outcomes, including preterm birth. In this systematic review, we summarize published epidemiologic cohort and case-control studies examining ozone exposures (estimated on a continuous scale) in early pregnancy (1st and 2nd trimesters (T1, T2)) and preterm birth using ratio measures, and perform a meta-analysis to evaluate the potential relationship between them. Studies were identified by searching PubMed and Web of Science, screened according to predefined inclusion/exclusion criteria, and evaluated for study quality. We extracted study data including effect estimates, confidence limits, study location, study years, ozone exposure assessment method, and mean or median ozone concentrations. Nineteen studies were identified and included, of

SUBMITTER: Rappazzo KM 

PROVIDER: S-EPMC8221456 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature