Subjective Responses to Alcohol in the Development and Maintenance of Alcohol Use Disorder.

ABSTRACT:

Objective

Alcohol use disorder (AUD) remains an urgent public health problem. Longitudinal data are needed to clarify the role of acute subjective responses to alcohol in the development and maintenance of excessive drinking and AUD. The authors report on 10 years of repeated examination of acute alcohol responses in the Chicago Social Drinking Project.

Methods

Young adult drinkers (N=190) participated in an initial alcohol challenge (0.8 g/kg of alcohol compared with placebo) that was repeated 5 and 10 years later. They were also assessed on drinking behavior and AUD symptoms at numerous intervals across the decade. Retention was high, as 184 of the 185 (99%) nondeceased active participants completed the 10-year follow-up, and 91% (163 of 179) of those eligible for alcohol

SUBMITTER: King A 

PROVIDER: S-EPMC8222099 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature