Resveratrol-loaded nanomedicines for cancer applications.

ABSTRACT:

Background

Resveratrol (3, 5, 4^' -trihydroxystilbene), a natural polyphenol and phytoalexin, has drawn considerable attention in the past decade due to its wide variety of therapeutic activities such as anticancer, anti-inflammatory, and antioxidant properties. However, its poor water solubility, low chemical stability, and short biological half-life limit its clinical utility.

Recent findings

Nanoparticles overcome the limitations associated with conventional chemotherapeutic drugs, such as limited availability of drugs to the tumor tissues, high systemic exposures, and consequent toxicity to healthy tissues. This review focuses on the physicochemical properties of resveratrol, the therapeutic potential of resveratrol nano-formulations, and the anticancer activit

SUBMITTER: Annaji M 

PROVIDER: S-EPMC8222557 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature